An ancient mitochondrial program tunes translation to haem availability

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10885-xAn evolutionarily conserved mitochondrial haem-sensing mechanism that predates the emergence of haemoglobin-based oxygen transport could have therapeutic value in …

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10885-x

An evolutionarily conserved mitochondrial haem-sensing mechanism that predates the emergence of haemoglobin-based oxygen transport could have therapeutic value in iron deficiency disorders.

A cholinergic hub in the nucleus accumbens gates opioid-reward learning

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10887-9Cell-type-specific opioid blockade in accumbal cholinergic interneurons abolishes morphine-reward learning without impairing analgesia and decouples morphine-evoke…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10887-9

Cell-type-specific opioid blockade in accumbal cholinergic interneurons abolishes morphine-reward learning without impairing analgesia and decouples morphine-evoked dopamine elevations from acetylcholine dips, suggesting pro-cholinergic strategies to limit early opioid reward acquisition.

Encapsulation epitaxy of air-stable 2D superconductors for quantum circuits

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10865-1An ‘encapsulation epitaxy’ mechanism is used to grow air-stable, two-dimensional superconducting films at the interface of a 2D–3D hybrid substrate, holding promis…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10865-1

An ‘encapsulation epitaxy’ mechanism is used to grow air-stable, two-dimensional superconducting films at the interface of a 2D–3D hybrid substrate, holding promise for use in fabrication of superconducting quantum circuitry.

A tumour-derived organoid biobank maps cancer gene dependencies

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10830-yA clinically annotated multi-omic organoid resource with matched tumour samples from 256 patients across 5 cancers maps gene dependencies, reveals subtype-specific…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10830-y

A clinically annotated multi-omic organoid resource with matched tumour samples from 256 patients across 5 cancers maps gene dependencies, reveals subtype-specific vulnerabilities and uncovers treatment-driven changes, expanding mechanistic insight and models for precision oncology.

An entangling gate for dual-rail erasure qubits

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10822-yA fast, low-error entangling gate for dual-rail cavity erasure qubits preserves a strong error hierarchy, advancing scalable quantum error correction with substant…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10822-y

A fast, low-error entangling gate for dual-rail cavity erasure qubits preserves a strong error hierarchy, advancing scalable quantum error correction with substantially improved fault-tolerant performance.

Pseudogap in a Fermi–Hubbard quantum simulator

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10875-zA cold-atom quantum simulator reveals the pseudogap metallic state in the Hubbard model, mapping its phase diagram and advancing understanding of doped Mott insula…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10875-z

A cold-atom quantum simulator reveals the pseudogap metallic state in the Hubbard model, mapping its phase diagram and advancing understanding of doped Mott insulators and high-temperature superconductivity.

Upcycling of polyvinyl chloride into polyalphaolefin lubricants

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10867-zA mild chemical process upcycles polyvinyl chloride waste into polyalphaolefin lubricants with tunable properties, offering an economical route to plastic recyclin…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10867-z

A mild chemical process upcycles polyvinyl chloride waste into polyalphaolefin lubricants with tunable properties, offering an economical route to plastic recycling and improved carbon circularity.

Virus reactivation in acute and long COVID-19

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10740-zChronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, …

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10740-z

Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prognostic potential.

A dependency map enhanced with next-generation 3D cancer models

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10843-7Integration of genome-scale CRISPR screening data from traditional cell lines and next-generation cancer models expands the representation of tumour subtypes and g…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10843-7

Integration of genome-scale CRISPR screening data from traditional cell lines and next-generation cancer models expands the representation of tumour subtypes and genomic alterations in The Cancer Dependency Map.