Month: September 2026

Phone-call tutorials improve learning cost-effectively during education emergencies

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02700-4Across five randomized trials in India, Kenya, Nepal, the Philippines and Uganda, weekly 20-minute mobile-phone-call tutorials produced large learning gains for…

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02700-4

Across five randomized trials in India, Kenya, Nepal, the Philippines and Uganda, weekly 20-minute mobile-phone-call tutorials produced large learning gains for primary-school children during school closures caused by the COVID-19 pandemic. Governments can keep children learning through societal shocks using this approach, which combines low-cost, high-access mobile-phone technology with high-quality tutoring targeted to each child’s learning level.

TRI-611, a selective, brain-penetrant molecular glue degrader of ALK

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10998-3TRI-611 induces the degradation of ALK fusion proteins via a previously undescribed CRBN recruitment motif, and its preclinical anti-tumour activity highlights …

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10998-3

TRI-611 induces the degradation of ALK fusion proteins via a previously undescribed CRBN recruitment motif, and its preclinical anti-tumour activity highlights TRI-611 as a potential new way of treating ALK-positive non-small-cell lung cancer.

Why we need an International Panel on Inequality

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02806-9Disparities in income and wealth are growing. A scientific assessment process can give governments the information they need to tackle them.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02806-9

Disparities in income and wealth are growing. A scientific assessment process can give governments the information they need to tackle them.

Imaging cellular activity across all organs reveals body-wide circuits

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10979-6An imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distribu…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10979-6

An imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distributed circuits.

Medicines do no good if people don’t take them

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02658-3Health psychologist Rob Horne explains why medication non-adherence is such a problem, and how behavioural science can help to address it.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02658-3

Health psychologist Rob Horne explains why medication non-adherence is such a problem, and how behavioural science can help to address it.

Predicting genome-wide functional constraints with GPN-Star

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11005-5GPN-Star, a genomic language model with a phylogeny-aware architecture for whole-genome alignment data, is shown to be a scalable and flexible tool for genetic …

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11005-5

GPN-Star, a genomic language model with a phylogeny-aware architecture for whole-genome alignment data, is shown to be a scalable and flexible tool for genetic variant effect prediction across species.

Drug-delivering particles aim to breach the blood–brain barrier

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02655-6The inability to get drugs into the brain has impeded the treatment of cancer and neurodegenerative diseases for decades. Techniques based on nanoparticles and …

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02655-6

The inability to get drugs into the brain has impeded the treatment of cancer and neurodegenerative diseases for decades. Techniques based on nanoparticles and exosomes are vying to provide a solution.

Ancient proteins identify various Denisovan remains from Southwest China

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10976-9Identification and proteomic analysis of bone fragments and teeth from an excavation in Southwest China provide insight into the evolution and phenotype of Deni…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10976-9

Identification and proteomic analysis of bone fragments and teeth from an excavation in Southwest China provide insight into the evolution and phenotype of Denisovans and fill a geographical gap in their documented distribution.