A first for CRISPR: powerful prime editing alters DNA directly in the human body

Nature, Published online: 22 October 2026; doi:10.1038/d41586-026-03371-xApplication of the high-precision technique is part of a clinical trial to treat a genetic disease that can cause liver and nerve damage.

Nature, Published online: 22 October 2026; doi:10.1038/d41586-026-03371-x

Application of the high-precision technique is part of a clinical trial to treat a genetic disease that can cause liver and nerve damage.

Can maths survive AI? Fields medallist Terence Tao calls for a ‘Maths 2.0’ world

Nature, Published online: 22 October 2026; doi:10.1038/d41586-026-03389-1As machines race ahead in solving problems, mathematicians must establish a new era that prizes human understanding over simply publishing more solutions.

Nature, Published online: 22 October 2026; doi:10.1038/d41586-026-03389-1

As machines race ahead in solving problems, mathematicians must establish a new era that prizes human understanding over simply publishing more solutions.

Daily briefing: The tell-tale features of a Denisovan

Nature, Published online: 22 October 2026; doi:10.1038/d41586-026-03438-9See what gave Denisovans their distinct look. Plus, a vaccine trial for Ebola could kick off this week in the Democratic Republic of the Congo and what makes a gr…

Nature, Published online: 22 October 2026; doi:10.1038/d41586-026-03438-9

See what gave Denisovans their distinct look. Plus, a vaccine trial for Ebola could kick off this week in the Democratic Republic of the Congo and what makes a great climate graphic.