Parkinson’s: beyond the brain

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03173-1Parkinson’s disease might develop in the gut before reaching the brain, and the environment could have a crucial role in triggering the disease.

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03173-1

Parkinson’s disease might develop in the gut before reaching the brain, and the environment could have a crucial role in triggering the disease.

Replacing the neurons that Parkinson’s destroys

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03166-0After decades of work, researchers have begun trialling transplants of dopamine neurons into people with the neurodegenerative disease — with early signs of succ…

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03166-0

After decades of work, researchers have begun trialling transplants of dopamine neurons into people with the neurodegenerative disease — with early signs of success.

How a once-controversial idea is advancing understanding of Parkinson’s disease

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03169-xThe disease is thought to be divided into two subtypes, depending on where it originates in the body — the gut or the brain.

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03169-x

The disease is thought to be divided into two subtypes, depending on where it originates in the body — the gut or the brain.

How the brain protects itself from Parkinson’s disease

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03171-3Brains are resilient. Harnessing their self-protective mechanisms might help to prevent or slow the progression of this neurodegenerative condition.

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03171-3

Brains are resilient. Harnessing their self-protective mechanisms might help to prevent or slow the progression of this neurodegenerative condition.

Clearing the way for a transformative stem-cell treatment for Parkinson’s disease

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03167-zMost Parkinson’s therapies aim to reduce the motor-control symptoms that the disease triggers. But stem-cell transplants in the brain could alter the disease at …

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03167-z

Most Parkinson’s therapies aim to reduce the motor-control symptoms that the disease triggers. But stem-cell transplants in the brain could alter the disease at a more fundamental level.

Fine-tuning brain stimulation to fight Parkinson’s disease

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03168-yNeuroscientists are developing a new type of brain implant that will decode every movement and symptom of people with this neurodegenerative condition, seeking b…

Nature, Published online: 04 November 2026; doi:10.1038/d41586-026-03168-y

Neuroscientists are developing a new type of brain implant that will decode every movement and symptom of people with this neurodegenerative condition, seeking better ways to ease symptoms.