How the US mid-term elections could shake up science

Nature, Published online: 29 October 2026; doi:10.1038/d41586-026-03479-0A Democratic victory in Congress could halt the Trump administration’s controversial grant-review plan and curb some of its funding actions.

Nature, Published online: 29 October 2026; doi:10.1038/d41586-026-03479-0

A Democratic victory in Congress could halt the Trump administration’s controversial grant-review plan and curb some of its funding actions.

Even stupendous black holes can’t explain dark matter

Nature, Published online: 29 October 2026; doi:10.1038/d41586-026-03386-4The theoretical objects would have left a larger imprint on cosmic radiation if they were a source of the invisible force pulling together the galaxies.

Nature, Published online: 29 October 2026; doi:10.1038/d41586-026-03386-4

The theoretical objects would have left a larger imprint on cosmic radiation if they were a source of the invisible force pulling together the galaxies.

Dengue comes back even in vaccinated people — new clues

Nature, Published online: 28 October 2026; doi:10.1038/d41586-026-03488-zResearchers help to answer a question dogging the development of improved vaccines against the mosquito-borne disease.

Nature, Published online: 28 October 2026; doi:10.1038/d41586-026-03488-z

Researchers help to answer a question dogging the development of improved vaccines against the mosquito-borne disease.

Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11170-7Cultures reveal conservation of cell structure, physical symbioses and anaerobiosis across Heimdallarchaeia (the archaeal lineage that branches closest to eukaryo…

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11170-7

Cultures reveal conservation of cell structure, physical symbioses and anaerobiosis across Heimdallarchaeia (the archaeal lineage that branches closest to eukaryotes) and other Promethearchaeota.

Pharmacological inhibition of METTL1 as a therapy against solid and blood cancers

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11178-zPharmacological inhibition of the m7G methyltransferase METTL1 in vivo impairs tumour growth and substantially prolongs survival in multiple mouse cancer models o…

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11178-z

Pharmacological inhibition of the m7G methyltransferase METTL1 in vivo impairs tumour growth and substantially prolongs survival in multiple mouse cancer models of different tissue origin.

Stone and water governed early human settlement of the desert

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11180-5A geoarchaeological survey of the Rub’ al Khali (the Empty Quarter of Arabia) and spatial modelling of the Arabian Peninsula suggest that human settlement tracked…

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11180-5

A geoarchaeological survey of the Rub’ al Khali (the Empty Quarter of Arabia) and spatial modelling of the Arabian Peninsula suggest that human settlement tracked the co-occurrence of water and stone suitable for making tools, rather than water alone.

Alzheimer’s disease genetics converges on microglial and neuronal dysregulation

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11206-yA multi-ancestry study of Alzheimer’s disease identifies new risk loci and potential drug targets, implicates microglia and neurons, and reveals a larger common-v…

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11206-y

A multi-ancestry study of Alzheimer’s disease identifies new risk loci and potential drug targets, implicates microglia and neurons, and reveals a larger common-variant contribution than previously estimated.