Additive manufacturing of ultralong and architected single crystals

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11185-0A free-form additive manufacturing method that uses alternating and pulsed heat inputs is described for fabricating metre-tall, centimetre-diameter single crystal…

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11185-0

A free-form additive manufacturing method that uses alternating and pulsed heat inputs is described for fabricating metre-tall, centimetre-diameter single crystals of Ti-6Al-4V, as well as hard-to-process refractory metals, including W, Mo, Nb and MoNb alloys.

Enzyme-embedded polyesters for accelerated biodegradation in the deep sea

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11192-1Near-complete deep-sea degradation of enzyme-embedded compostable polyesters shows that thermal enzyme embedding greatly accelerates breakdown across marine envir…

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11192-1

Near-complete deep-sea degradation of enzyme-embedded compostable polyesters shows that thermal enzyme embedding greatly accelerates breakdown across marine environments while preserving material performance, offering a promising strategy to mitigate persistent ocean plastic pollution.

Multimodal precision diagnostics in clinical xenotransplantation

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional diagnostics often…

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0

Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional diagnostics often miss; a multimodal precision diagnostic framework is proposed to detect these injuries earlier, guide personalized immunosuppression and inform future gene editing strategies.

Drought and disease trigger novel interactions among top predators

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11194-zClimate-driven drought and prey decline triggered lynx predation on raptors, reducing raptor fitness and abundance and producing cascading effects across lower tr…

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11194-z

Climate-driven drought and prey decline triggered lynx predation on raptors, reducing raptor fitness and abundance and producing cascading effects across lower trophic levels.

Functional architecture of the human insula

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11175-2A functional architecture of the human insula links cytoarchitecture to directed and asymmetric electrophysiological interactions, with mechanistic implications f…

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11175-2

A functional architecture of the human insula links cytoarchitecture to directed and asymmetric electrophysiological interactions, with mechanistic implications for cognitive modulation of pain and interoceptive experience.

Amazon carbon emissions driven by human actions amplified by droughts

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11168-1Fifteen years of atmospheric CO2 measurements show that the Amazon carbon sink is weakening, with fires, deforestation and climate stress driving increasingly hig…

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11168-1

Fifteen years of atmospheric CO2 measurements show that the Amazon carbon sink is weakening, with fires, deforestation and climate stress driving increasingly high carbon emissions.

Fabric user interface can be worn on your sleeve — and machine-washed

Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03064-5Touch-sensitive, light-emitting yarn can turn everyday clothing into washable, bendable user interfaces with dynamic graphics and versatile computing functions.

Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03064-5

Touch-sensitive, light-emitting yarn can turn everyday clothing into washable, bendable user interfaces with dynamic graphics and versatile computing functions.

Programmable design of functional proteins from natural language

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11205-zPinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validate…

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11205-z

Pinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validated activities and improved CO2-fixation product yields without iterative optimization.