Nature, Published online: 04 November 2026; doi:10.1038/s41586-026-11210-2
structRFM, a structure-guided RNA foundation model pre-trained on 21 million sequence–structure pairs, learns multimodal representations that improve secondary and tertiary structure prediction, functional inference and zero-shot generalization across diverse RNA families.An open structure-guided RNA foundation model for generalizable prediction
Nature, Published online: 04 November 2026; doi:10.1038/s41586-026-11210-2structRFM, a structure-guided RNA foundation model pre-trained on 21 million sequence–structure pairs, learns multimodal representations that improve secondary a…