Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10647-9
In Streptomyces spp., a conserved biosynthetic gene megacluster produces an arsenal of distinct antimicrobials that converge on bacterial biotin biosynthesis as a naturally evolved combination therapy.A <i>Streptomyces</i> megacluster encodes synergistic biotin-targeting antibiotics
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10647-9In Streptomyces spp., a conserved biosynthetic gene megacluster produces an arsenal of distinct antimicrobials that converge on bacterial biotin biosynthesis as a na…