Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10670-w
By pairing two neural networks in an iterative optimization algorithm, small-molecule binding proteins can be designed from scratch with high accuracy, affinity and success rates, showing promise for applications in drug delivery and sequestration.Zero-shot design of drug-binding proteins via neural iterative selection−expansion
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10670-wBy pairing two neural networks in an iterative optimization algorithm, small-molecule binding proteins can be designed from scratch with high accuracy, affinity and …