The mutational landscape of STING-induced immunity

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10685-3A massively parallel assay systematically charts the sequence-function landscape of the STING signalling protein, and the findings define molecular principles that t…

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10685-3

A massively parallel assay systematically charts the sequence-function landscape of the STING signalling protein, and the findings define molecular principles that tune STING activity and show its functional potential across immune contexts.