Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10641-1
Integrated multi-omic profiling of glioblastoma reveals GPNMB as a shared antigen in tumour cells and the surrounding microenvironment, and GPNMB-targeted chimeric antigen receptor T cells demonstrate therapeutic activity in vitro and in animal models.Dual tumour–myeloid targeting of glioblastoma with GPNMB CAR-T cells
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10641-1Integrated multi-omic profiling of glioblastoma reveals GPNMB as a shared antigen in tumour cells and the surrounding microenvironment, and GPNMB-targeted chimeric a…