Heat-triggered phospholipid flipping stabilizes plasma membrane fluidity

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10726-xIn rice, the P4-ATPase complex OsALA5–OsALIS2 rapidly stabilizes membrane fluidity in response to high temperature by flipping saturated phosphatidylcholines to the …

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10726-x

In rice, the P4-ATPase complex OsALA5–OsALIS2 rapidly stabilizes membrane fluidity in response to high temperature by flipping saturated phosphatidylcholines to the cytosolic leaflet of the plasma membrane.