Genetic background sets the trajectory of experimental cancer evolution

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10821-zExperimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving muta…

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10821-z

Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in shaping the earliest stages of cancer development.