Membranolytic peptide programs immunogenic cell death for cancer therapy

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10899-5The synthetic-acid-responsive membranolytic peptide aMPC16-CA50 induces immunogenic membranolytic cell death in tumour cells, robustly potentiating immune checkpoi…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10899-5

The synthetic-acid-responsive membranolytic peptide aMPC16-CA50 induces immunogenic membranolytic cell death in tumour cells, robustly potentiating immune checkpoint blockade therapy.