Nature, Published online: 12 August 2026; doi:10.1038/s41467-026-76680-4
Spike mutations in SARS-CoV-2 Omicron variants impact vaccine-mediated protection. In this study, the authors identify mutations that also alter spike cleavage and virus entry and that these Omicron mutations reshape both pathogenesis and transmission outcomes.Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection
Nature, Published online: 12 August 2026; doi:10.1038/s41467-026-76680-4Spike mutations in SARS-CoV-2 Omicron variants impact vaccine-mediated protection. In this study, the authors identify mutations that also alter spike cleavage and…