Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10903-y
Cryo-electron microscopy structures show how IS621 bridge recombinase mediates DNA excision, explaining its natural preference for insertion and informing the design of programmable bridge-editing technologies.Structural mechanism governing the directionality of bridge recombination
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10903-yCryo-electron microscopy structures show how IS621 bridge recombinase mediates DNA excision, explaining its natural preference for insertion and informing the desi…