Topographic structure and function of locus coeruleus noradrenaline neurons

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11026-0Dorsal and ventral noradrenergic neurons in the locus coeruleus form topographic subpopulations whose projection patterns and activity encode choice switching, …

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11026-0

Dorsal and ventral noradrenergic neurons in the locus coeruleus form topographic subpopulations whose projection patterns and activity encode choice switching, reward-prediction errors and disregard of reward-predictive cues, supporting flexible learning behaviour.