Single-nucleus transcriptome-wide association study of human brain disorders

Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-10836-6Single-nucleus transcriptomics across diverse populations is used to explore how genetic risk for brain disorders affects specific cell types, revealing previou…

Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-10836-6

Single-nucleus transcriptomics across diverse populations is used to explore how genetic risk for brain disorders affects specific cell types, revealing previously hidden gene–trait associations and conserved, cell-type-specific mechanisms.