Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-11029-x
In Drosophila, the protein Lsp2, which is induced by dietary essential amino acids, is a key physiological effector of mTORC1, and mutant flies that lack the Lsp2 gene exhibit reduced translation of TOP mRNAs and improved longevity.Lsp2 links mTORC1 to TOP mRNA translation and lifespan in <i>Drosophila</i>
Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-11029-xIn Drosophila, the protein Lsp2, which is induced by dietary essential amino acids, is a key physiological effector of mTORC1, and mutant flies that lack the Ls…