Lsp2 links early-life diet to adult translation and lifespan in <i>Drosophila</i>

Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-11031-3Isotope tracing is used to determine the fate of larval dietary amino acids in adult flies, and identifies Lsp2 as a key regulator of translation and lifespan t…

Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-11031-3

Isotope tracing is used to determine the fate of larval dietary amino acids in adult flies, and identifies Lsp2 as a key regulator of translation and lifespan that forms the molecular basis of the effects of early-life protein restriction.