Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1
A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells.Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism
Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while…