Month: August 2026

Degree-of-polarization modulation for high-dimensional optical computing

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10891-zBy engineering the statistics of light at the micrometre scale using phase-only spatial light modulators, both the state and degree of polarization become spatiall…

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10891-z

By engineering the statistics of light at the micrometre scale using phase-only spatial light modulators, both the state and degree of polarization become spatially programmable, enabling direct encoding of information in a high-dimensional space.

Temporal uncoupling of radial glia lineage progression in cortical organoids

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10916-7RGP lineage tracing in stem-cell-derived organoids shows highly plastic proliferation and reduced clonal neuronal diversity, indicating that missing non-cell-auton…

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10916-7

RGP lineage tracing in stem-cell-derived organoids shows highly plastic proliferation and reduced clonal neuronal diversity, indicating that missing non-cell-autonomous niche cues are essential for faithful temporal control of cortical lineage progression.

Luminescent-reaction-enabled super-resolution imaging

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10889-7A new chemistry-based super-resolution imaging framework is described, enabling 3D, laser-free, highly sensitive and ultralong-term imaging of live cells which ove…

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10889-7

A new chemistry-based super-resolution imaging framework is described, enabling 3D, laser-free, highly sensitive and ultralong-term imaging of live cells which overcomes the limitations in spatiotemporal resolution associated with reaction-based imaging methods.

Agentic profiles for effective AI governance

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10805-zA framework comprising four dimensions—autonomy, efficacy, goal complexity and generality—is proposed for characterizing AI agents, supporting the construction of …

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10805-z

A framework comprising four dimensions—autonomy, efficacy, goal complexity and generality—is proposed for characterizing AI agents, supporting the construction of agentic profiles for the effective governance of different AI agents.

Neural basis of compositional control

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10896-8Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, ante…

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10896-8

Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating policy switches and orbitofrontal cortex supplying value-based contextualization rather than driving continuous policy updating.

Glucose-responsive probiotics for glycaemic modulation in mice and monkeys

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10909-6Engineered probiotics equipped with a synthetic glucose-responsive circuit transiently colonize the gut and secrete therapeutic factors when glucose levels increas…

Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10909-6

Engineered probiotics equipped with a synthetic glucose-responsive circuit transiently colonize the gut and secrete therapeutic factors when glucose levels increase, enabling safe, oral, sense-and-respond control of diabetes in mouse and primate models.