The Virtual Tissues foundation model resolves spatial proteomics across scales

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10884-yVirtual Tissues (VirTues), a foundation model for spatial proteomics that captures tissue organization across scales, supports marker reconstruction, cell segmenta…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10884-y

Virtual Tissues (VirTues), a foundation model for spatial proteomics that captures tissue organization across scales, supports marker reconstruction, cell segmentation and typing, niche annotation, spatial biomarker discovery and patient stratification across heterogeneous panels and datasets.

<b>Junk plastic turns into high-value commodity with chemistry trick</b>

Nature, Published online: 05 August 2026; doi:10.1038/d41586-026-02445-0Researchers untangle the chemistry behind turning PVC into high-grade motor lubricant — plus, how engineered yeast can help make a cancer drug.

Nature, Published online: 05 August 2026; doi:10.1038/d41586-026-02445-0

Researchers untangle the chemistry behind turning PVC into high-grade motor lubricant — plus, how engineered yeast can help make a cancer drug.

An expanded codebook of human transcription factor DNA-binding specificity

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10798-9Results from a panel of assays that analyse different aspects of DNA sequence specificity reveal more than 100 new motifs to aid the characterization of putative h…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10798-9

Results from a panel of assays that analyse different aspects of DNA sequence specificity reveal more than 100 new motifs to aid the characterization of putative human transcription factors.

ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10890-0The RNA-binding protein ZFP36L2 mediates stress-adaptive plasticity in intestinal regeneration and colorectal cancer metastasis.

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10890-0

The RNA-binding protein ZFP36L2 mediates stress-adaptive plasticity in intestinal regeneration and colorectal cancer metastasis.

Ubiquitous Kelvin–Helmholtz instabilities driving plasma mixing on the Sun

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10871-3High-spatial-resolution observations of the solar photosphere reveal a far more complex and dynamic solar scene than previously observed and show that ubiquitous K…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10871-3

High-spatial-resolution observations of the solar photosphere reveal a far more complex and dynamic solar scene than previously observed and show that ubiquitous Kelvin–Helmholtz instabilities drive plasma mixing on the Sun.

Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10874-0Amygdala astrocyte primary cilia are disrupted during stress, and their restoration leads to improvements in stress-related behaviour in mice.

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10874-0

Amygdala astrocyte primary cilia are disrupted during stress, and their restoration leads to improvements in stress-related behaviour in mice.

In situ particle-to-fibre transformation of hydrogels for 3D printing

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10883-zA three-dimensional printing method transforms hydrogel particles into aligned microfibres during extrusion, creating structural anisotropy to accelerate muscle ti…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10883-z

A three-dimensional printing method transforms hydrogel particles into aligned microfibres during extrusion, creating structural anisotropy to accelerate muscle tissue regeneration.

Membranolytic peptide programs immunogenic cell death for cancer therapy

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10899-5The synthetic-acid-responsive membranolytic peptide aMPC16-CA50 induces immunogenic membranolytic cell death in tumour cells, robustly potentiating immune checkpoi…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10899-5

The synthetic-acid-responsive membranolytic peptide aMPC16-CA50 induces immunogenic membranolytic cell death in tumour cells, robustly potentiating immune checkpoint blockade therapy.

Uncovering the mechanism of female restitution in sugarcane hybrids

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10863-3Female restitution in interspecific sugarcane hybrids between Saccharum officinarum and Saccharum spontaneum arises from second division restitution, as haplotype-…

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10863-3

Female restitution in interspecific sugarcane hybrids between Saccharum officinarum and Saccharum spontaneum arises from second division restitution, as haplotype-resolved F1 genomes reveal duplicated, partially recombined maternal chromatids and distinctive recombination signatures, resolving its meiotic mechanism and enabling breeding strategies to accelerate crop improvement.