Month: September 2026

Self-aligned optical microcomb emerging between octave-separated lasers

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11086-2An architectural inversion shifts integrated optical frequency comb generation from outward broadening around a central pump to filling the spectrum between two…

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11086-2

An architectural inversion shifts integrated optical frequency comb generation from outward broadening around a central pump to filling the spectrum between two octave-separated pumps through a self-aligned parametrically driven cavity soliton, enabling robust self-referencing for future deployable on-chip frequency and time metrology.

X-ray liquidography decodes complex motions in azobenzene isomerization

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11068-4Time-resolved X-ray liquidography films the structural changes of azobenzene during trans-to-cis isomerization in solution with atomic-level precision.

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11068-4

Time-resolved X-ray liquidography films the structural changes of azobenzene during trans-to-cis isomerization in solution with atomic-level precision.

Evolution of terrestrial anatomy revealed by a derived stem tetrapod

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11090-6New anatomical evidence reclassifies Westlothiana as an aquatic stem tetrapod, showing that terrestrial limb adaptations evolved mosaically in transitional amph…

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11090-6

New anatomical evidence reclassifies Westlothiana as an aquatic stem tetrapod, showing that terrestrial limb adaptations evolved mosaically in transitional amphibious environments before crown tetrapods emerged.

Global mangrove distribution on the open coast is controlled by waves

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11089-zA process-driven mangrove presence or absence model using 20 years of open-source wave data shows that wave conditions are critical in determining where mangrov…

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11089-z

A process-driven mangrove presence or absence model using 20 years of open-source wave data shows that wave conditions are critical in determining where mangroves grow worldwide.

Spatiotemporal clonal architecture of the newborn mouse forebrain

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11064-8Clonal barcoding across the newborn mouse forebrain reveals developmental principles whereby glutamatergic neurons and astrocytes remain locally derived, wherea…

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11064-8

Clonal barcoding across the newborn mouse forebrain reveals developmental principles whereby glutamatergic neurons and astrocytes remain locally derived, whereas widely dispersed GABAergic (γ-aminobutyric acid-producing) lineages link neurons with oligodendrocyte precursor cells.

Type 2 immune history trains lung macrophages for viral disease tolerance

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11060-yType 2 inflammation trains nerve- and airway-associated macrophages to confer disease tolerance against lethal influenza by limiting immunopathology and promoti…

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11060-y

Type 2 inflammation trains nerve- and airway-associated macrophages to confer disease tolerance against lethal influenza by limiting immunopathology and promoting tissue repair without enhancing viral clearance.

GPCR antagonism via rewiring of receptor trafficking and degradation

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11088-0A strategy for functional G-protein-coupled receptor (GPCR) antagonism through bispecific antibody-mediated endocytosis and lysosomal degradation is reported.

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11088-0

A strategy for functional G-protein-coupled receptor (GPCR) antagonism through bispecific antibody-mediated endocytosis and lysosomal degradation is reported.

Written in development and lost in ageing: the grammar of cellular identity

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-10955-0Ageing reflects progressive decanalization of mammalian cell identity, driven by erosion of a regulatory grammar written during development.

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-10955-0

Ageing reflects progressive decanalization of mammalian cell identity, driven by erosion of a regulatory grammar written during development.

Prion-like transmission of human tau strains in the mouse brain

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11061-xMouse experiments show that Alzheimer’s disease and corticobasal degeneration tau filaments retain their distinct structures during templated seeding, supportin…

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11061-x

Mouse experiments show that Alzheimer’s disease and corticobasal degeneration tau filaments retain their distinct structures during templated seeding, supporting strain-specific tau propagation and disease modelling.