Month: September 2026

A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11002-8SERPINE1 and SERPINB2-driven fibrin-rich niches locally programme immunosuppressive macrophages and exclude T cells, enabling spatially organized immune evasion…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11002-8

SERPINE1 and SERPINB2-driven fibrin-rich niches locally programme immunosuppressive macrophages and exclude T cells, enabling spatially organized immune evasion in pancreatic ductal carcinoma.

‘Superdark’ protein looks like a G-protein-coupled receptor — but shows unconventional behaviour

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02472-xMining millions of AI-predicted structures reveals an evolutionarily conserved protein that resembles a receptor family member but functions differently.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02472-x

Mining millions of AI-predicted structures reveals an evolutionarily conserved protein that resembles a receptor family member but functions differently.

Denisovans from southwestern China and their subsistence strategies

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their eco…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4

Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their ecology, behaviour and cultural legacy in eastern Asia.

Genetic associations with the Big Five personality traits probed in one million people

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02790-0Human DNA has been linked to personality traits — how individuals think, feel and act — thus identifying hundreds of genetic variants that contribute to the tra…

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02790-0

Human DNA has been linked to personality traits — how individuals think, feel and act — thus identifying hundreds of genetic variants that contribute to the traits’ moderate heritability. The pathways from DNA to personality are robust yet complex, with widespread relevance for health, wealth, work and love.

Advancing conflict research and response through satellite-derived data

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11004-6Integrating satellite-derived war-damage data with text-based fatality records through improvement, enrichment and fusion mitigates limitations inherent in each…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11004-6

Integrating satellite-derived war-damage data with text-based fatality records through improvement, enrichment and fusion mitigates limitations inherent in each source, revealing complex violence dynamics beyond fatality-centric paradigms, as case studies from Ukraine and Myanmar illustrate.

Foaming photopolymers as a high-resolution biomimetic printing platform

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10968-9Deep-foam photolithography uses light-controlled polymer foaming to create high-resolution, multifunctional microstructures with tunable optical, wetting and fl…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10968-9

Deep-foam photolithography uses light-controlled polymer foaming to create high-resolution, multifunctional microstructures with tunable optical, wetting and fluid-handling properties for advanced manufacturing applications.

Phone tutoring boosts math scores when schools are forced to close

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02843-4Evidence suggests that regular calls can keep kids learning when schooling is disrupted — plus, why a familiar world map may be about to change.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02843-4

Evidence suggests that regular calls can keep kids learning when schooling is disrupted — plus, why a familiar world map may be about to change.

PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10954-1A specific population of macrophages that express high levels of the enzyme PLA2G2D in tumour-draining lymph nodes is associated with poor prognosis in patients…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10954-1

A specific population of macrophages that express high levels of the enzyme PLA2G2D in tumour-draining lymph nodes is associated with poor prognosis in patients, and inhibiting PLA2G2D improves anti-tumour immunity in mouse models.

Use AI as a sparring partner, not an oracle

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02846-1As artificial-intelligence tools become crucial collaborators in science, universities must teach students to challenge such systems and assess their ability to…

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02846-1

As artificial-intelligence tools become crucial collaborators in science, universities must teach students to challenge such systems and assess their ability to do so.