Month: September 2026

Within-family effect of ancestry on complex traits in a Mexican population

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11039-9This study uses a within-family design to identify significant ancestry differences in complex traits such as height and type 2 diabetes in a genetically divers…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11039-9

This study uses a within-family design to identify significant ancestry differences in complex traits such as height and type 2 diabetes in a genetically diverse population from Mexico City.

Breaking timescales with generative sampling of conformational transitions

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11025-1A generative committor-guided path-sampling framework reconstructs rare biomolecular transition pathways and reveals the underlying thermodynamics and kinetics …

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11025-1

A generative committor-guided path-sampling framework reconstructs rare biomolecular transition pathways and reveals the underlying thermodynamics and kinetics without using predefined collective variables or brute-force sampling, at an acceptable computational cost.

An operational perturbation proteomics-based virtual cell model

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11001-9Temporal protein-abundance measurements from systematically perturbed breast cancer cell lines were generated to develop ProteinTalks, a virtual cell model that…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11001-9

Temporal protein-abundance measurements from systematically perturbed breast cancer cell lines were generated to develop ProteinTalks, a virtual cell model that functions as an operational tool for diverse drug discovery tasks.

Neocortical long-range inhibition promotes cortical synchrony and sleep

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10876-yIn mice, a sparse population of sleep-active long-range inhibitory neurons in the neocortex promote widespread cortical synchronization and sleep, revealing a c…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10876-y

In mice, a sparse population of sleep-active long-range inhibitory neurons in the neocortex promote widespread cortical synchronization and sleep, revealing a cortical mechanism that contributes to the regulation of sleep.

Electric charge makes drops of water more destructive

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02705-zIn many real-world settings, water droplets can become slightly charged as they slide across solid surfaces. This charge has been found to enable water droplets…

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02705-z

In many real-world settings, water droplets can become slightly charged as they slide across solid surfaces. This charge has been found to enable water droplets to damage protective coatings more easily than uncharged droplets do, and to cause the underlying metal to corrode.

DeepMind’s new genome ‘atlas’ charts effects of all nine billion human gene mutations

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02835-4AI model AlphaGenome forecasts the consequences of altering every single DNA letter in the human genome.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02835-4

AI model AlphaGenome forecasts the consequences of altering every single DNA letter in the human genome.

Popular open-science platform to stop hosting data and code amid funding concerns

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02598-yChanges to the Open Science Framework’s policies will come into effect in November, forcing researchers to reconsider their workflows.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02598-y

Changes to the Open Science Framework’s policies will come into effect in November, forcing researchers to reconsider their workflows.

These six advances could change how drugs are delivered

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02654-7Medication triggered by your circadian clock, self-assembling delivery systems based on DNA and other highlights from studies and trials.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02654-7

Medication triggered by your circadian clock, self-assembling delivery systems based on DNA and other highlights from studies and trials.