DNA-editing ‘pencils’ probe early human development

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02840-7A genome-rewriting approach known as adenine base editing offers a precise way to investigate gene function in early human embryos.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02840-7

A genome-rewriting approach known as adenine base editing offers a precise way to investigate gene function in early human embryos.

Mobile education builds resilience during shocks in five countries

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10990-xRemote phone-based targeted tutoring in five countries produced large, cost-effective learning gains during school closures, outperforming text messaging and wo…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10990-x

Remote phone-based targeted tutoring in five countries produced large, cost-effective learning gains during school closures, outperforming text messaging and working effectively when delivered by governments or non-governmental organizations to strengthen education resilience.

A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11002-8SERPINE1 and SERPINB2-driven fibrin-rich niches locally programme immunosuppressive macrophages and exclude T cells, enabling spatially organized immune evasion…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11002-8

SERPINE1 and SERPINB2-driven fibrin-rich niches locally programme immunosuppressive macrophages and exclude T cells, enabling spatially organized immune evasion in pancreatic ductal carcinoma.

‘Superdark’ protein looks like a G-protein-coupled receptor — but shows unconventional behaviour

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02472-xMining millions of AI-predicted structures reveals an evolutionarily conserved protein that resembles a receptor family member but functions differently.

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02472-x

Mining millions of AI-predicted structures reveals an evolutionarily conserved protein that resembles a receptor family member but functions differently.

Denisovans from southwestern China and their subsistence strategies

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their eco…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4

Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their ecology, behaviour and cultural legacy in eastern Asia.

Genetic associations with the Big Five personality traits probed in one million people

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02790-0Human DNA has been linked to personality traits — how individuals think, feel and act — thus identifying hundreds of genetic variants that contribute to the tra…

Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02790-0

Human DNA has been linked to personality traits — how individuals think, feel and act — thus identifying hundreds of genetic variants that contribute to the traits’ moderate heritability. The pathways from DNA to personality are robust yet complex, with widespread relevance for health, wealth, work and love.

Advancing conflict research and response through satellite-derived data

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11004-6Integrating satellite-derived war-damage data with text-based fatality records through improvement, enrichment and fusion mitigates limitations inherent in each…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11004-6

Integrating satellite-derived war-damage data with text-based fatality records through improvement, enrichment and fusion mitigates limitations inherent in each source, revealing complex violence dynamics beyond fatality-centric paradigms, as case studies from Ukraine and Myanmar illustrate.

Foaming photopolymers as a high-resolution biomimetic printing platform

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10968-9Deep-foam photolithography uses light-controlled polymer foaming to create high-resolution, multifunctional microstructures with tunable optical, wetting and fl…

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10968-9

Deep-foam photolithography uses light-controlled polymer foaming to create high-resolution, multifunctional microstructures with tunable optical, wetting and fluid-handling properties for advanced manufacturing applications.