Month: August 2026

Observation of conformal field theory spectra in a quantum simulator

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10904-xMeasurements on an array of optically trapped neutral atoms at a quantum phase transition provide a direct observation of the universal excitation spectrum predict…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10904-x

Measurements on an array of optically trapped neutral atoms at a quantum phase transition provide a direct observation of the universal excitation spectrum predicted by conformal field theory.

Functional role of skull lymphoid structures in CNS immunosurveillance

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10951-4Functional lymphoid structures within the skull bone marrow enable central nervous system immunosurveillance and shape immune responses to brain disease.

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10951-4

Functional lymphoid structures within the skull bone marrow enable central nervous system immunosurveillance and shape immune responses to brain disease.

Increasing CO<sub>2</sub> levels fertilize C<sub>4</sub> grass production

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10935-4By combining a meta-analysis of CO2 enrichment experiments with three decades of southern African savanna observations, an increase in biomass production by C4 gra…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10935-4

By combining a meta-analysis of CO2 enrichment experiments with three decades of southern African savanna observations, an increase in biomass production by C4 grasses under rising CO2 levels in water-limited environments is revealed.

Wake-activated neuronal populations that regulate sleep drive

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10928-3Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep dri…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10928-3

Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently reduce daily sleep amount.

Safety and security of large language models in healthcare

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10687-1The Review examines rapid LLM adoption in clinical care, outlining emerging security and safety risks across development stages, key protective layers, clinically …

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10687-1

The Review examines rapid LLM adoption in clinical care, outlining emerging security and safety risks across development stages, key protective layers, clinically relevant threats and current mitigation responsibilities in a single integrated framework.

Psychedelics align brain activity with context

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10910-zThe psychedelic psilocybin reorganizes brain activity into structured, context-aligned patterns that integrate internal and external processing, providing a neural…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10910-z

The psychedelic psilocybin reorganizes brain activity into structured, context-aligned patterns that integrate internal and external processing, providing a neural basis for the felt continuity between self and world, elucidating how the psychedelic state translates into psychological change.

Atomic-scale double-slit interferometry with a focused electron probe

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10914-9Double-slit interferometry at the atomic scale is demonstrated using scanning transmission electron microscopy to provide evidence of interference fringes generate…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10914-9

Double-slit interferometry at the atomic scale is demonstrated using scanning transmission electron microscopy to provide evidence of interference fringes generated with a focused electron beam encountering two silicon atomic columns separated by 1.36 Å.

A biased allosteric modulator is a molecular glue for β<sub>2</sub>AR dimerization

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10892-yAP-7-168, an optimized derivative of a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR), functions as a molecular glue to stabi…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10892-y

AP-7-168, an optimized derivative of a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR), functions as a molecular glue to stabilize β2AR homodimerization.

Human brain organoids record the passage of time over multiple years

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10877-xHuman brain organoids were developed for over five years in culture to demonstrate that brain cells can continue to mature and record the passage of time, followin…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10877-x

Human brain organoids were developed for over five years in culture to demonstrate that brain cells can continue to mature and record the passage of time, following human-specific endogenous programs, even outside the context of the organism.

Synthesis of pyrroles from isoxazoles by an O-to-C skeletal edit

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a co…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6

A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a computational model predicting reaction outcomes.