Atomic-scale double-slit interferometry with a focused electron probe

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10914-9Double-slit interferometry at the atomic scale is demonstrated using scanning transmission electron microscopy to provide evidence of interference fringes generate…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10914-9

Double-slit interferometry at the atomic scale is demonstrated using scanning transmission electron microscopy to provide evidence of interference fringes generated with a focused electron beam encountering two silicon atomic columns separated by 1.36 Å.

A biased allosteric modulator is a molecular glue for β<sub>2</sub>AR dimerization

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10892-yAP-7-168, an optimized derivative of a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR), functions as a molecular glue to stabi…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10892-y

AP-7-168, an optimized derivative of a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR), functions as a molecular glue to stabilize β2AR homodimerization.

Human brain organoids record the passage of time over multiple years

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10877-xHuman brain organoids were developed for over five years in culture to demonstrate that brain cells can continue to mature and record the passage of time, followin…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10877-x

Human brain organoids were developed for over five years in culture to demonstrate that brain cells can continue to mature and record the passage of time, following human-specific endogenous programs, even outside the context of the organism.

Synthesis of pyrroles from isoxazoles by an O-to-C skeletal edit

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a co…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6

A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a computational model predicting reaction outcomes.

Multiyear tropical warm pool warming drives slowdown in Antarctic mass loss

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10912-xRecent Antarctic ice mass gain was linked to a recurrent atmospheric teleconnection, but this recurs about once per decade in observations and historical simulatio…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10912-x

Recent Antarctic ice mass gain was linked to a recurrent atmospheric teleconnection, but this recurs about once per decade in observations and historical simulations so does not yet reflect a global-warming-driven moistening of Antarctica.